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- BY: DR. KHURRAM ZAFAR
- www.thedentalclinicpk.com
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- The Acidogenic theory
- The Proteolytic theory
- Proteolysis chelation theory
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- W.D Miller was the first well known scientist and investigator of dental
caries and published his results in 1882.
- According to him dental decay is a chemoparasitic process
- It is a two stage process there is decalcification of the enamel which
also results in the destruction of the dentin. in the second stage there
is dissolution of the softened residue of the enamel and dentin.
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- In the first stage there is destruction is done by the acid attack where
as the dissolution of the residue is carried by the proteolytic action
of the bacteria's
- This whole process is supported by the presence of carbohydrates
microorganisms and dental plaque
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- The evidence given by the acidogenic theory was considerable but it was
not conclusive, and alternative explanation was given in the form of
proteolytic theory.
- Workers like “Heider, Bodecker (1878)and Abbott (1879) contributed
considerably to this theory
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- There has been evidence that the organic portion of the tooth plays an important role in the
development of dental caries
- The are some enamel structure which are made of the organic material
such enamel lamelle and enamel rods
- These structure prove to be the path ways for the advancing
microorganisms.
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- It has been established that enamel contains 0.56 % of organic matter of
which 0.18% is keratin and 0.17 % is a soluble protein
- Microorganisms invade the enamel lamelle and the acid produced by the
bacteria's causes damage to the organic pathways in advance
- The production of the yellowish pigment produced by the proteolytic
bacteria’s the presence of this pigment was only possible in the
presence of dietary carbohydrates.
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- Some of the minor flaws of the acidogenic and the proteolytic theory
were addressed in the proteolysis chelation theory.
- This theory was put forward by Schatz and his co-workers .
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- CHELATION
- It is a process in which
there is complexing of the metal ions to form complex substance through
coordinate covalent bond which results in:
- poorly
dissociated /or
- weakly ionized
compound
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- Example of chelation reaction:
- Hemoglobin in which 4 pyrrole
nuclei are linked to iron by a
similar bond
- Chelation is independent of the
PH of the medium.
- The bacteria’s attack on the surface of the enamel this is initiated by
keratinolytic microorganisms this result in the breakdown of the protein
chiefly keratin and results in the formation of soluble chelates which
decalcify enamel even at neutral PH
- Mucopolysaccarides may also act as secondary chelators.
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- Gv blanks classification of caries class
- I , II , III , IV , V and VI
- Rampant caries
- Recurrent caries
- Arrested caries
- Root or cemental caries
- Baby bottle caries
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